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Consultant Scientist in Andrology

Matt Tomlinson (PhD)

Matt is our lead expert and has over 30 years’ experience in the field within NHS Assisted Conception Services, a lecturer and teacher for Masters-level courses and as a trainer for professional bodies.


His experience started with running laboratory courses for the British Andrology Society (BAS) and then the Association of Biomedical Andrologists, a group he was a co-founder of. 


Matt has been a peer-assessor for accreditation, an expert witness for a number of high profile legal cases, has been a reviewer for a number of journals and grant awarding bodies and has over 50 peer-reviewed papers and book chapters. 

Andrology Consulting

His main areas are in: assessing/preparing validating/ verifying  procedures with a view to accreditation; risk management of the diagnostic and therapeutic service; cryopreservation (sperm banking) services and developing automation in semen analysis. He is an advocate for evidence-based diagnostics and treatment for infertility. Although professional groups have attempted to standardise manual semen analysis, the evidence continues to demonstrate a lack of  reproducibility and as a result has generally poor clinical value. This has in part provided the motivation to improve matters and one result is SAMi, a CASA (Computer Assisted Semen Analysis) system, which he co-invented. SAMi is very user-friendly and provides reliable and reproducible sperm count, motility and velocity and in a fraction of the time taken manually. If Matt can't help then he he will know someone who can.



  • Tomlinson M, Igbokwe N (2020) The Use of Radio Frequency Identification (RFID) and Track and Trace Technology in Reducing the Risks and Cost of Sperm Cryopreservation. Ann Clin Lab Res. Vol.8 No.1:308 doi:10.36648/2386-5180.8.1.308

  • Sumner RN1,2, Tomlinson M3, Craigon J4, England GCW1, Lea RG5. Independent and combined effects of diethylhexyl phthalate and polychlorinated biphenyl 153 on sperm quality in the human and dog. Sci Rep. 2019 Mar 4;9(1):3409. doi: 10.1038/s41598-019-39913-9.

  • Tomlinson MJ (2018).  Review:  Safe storage of gametes and embryos: no time for complacency. Seminars in Reproduction, and Medicine 36(05): 289-298

  • Tomlinson MJ, Kohut T, Pooley K and Atkinson M (2019). Is azoospermia the appropriate standard for post-vasectomy semen analysis? Or an unachievable goal of best practice guidelines Human Fertility,  Human Fertility 23(4):1-7

  • Tomlinson MJ and Naeem A (2018). Computer-aided sperm analysis (CASA) in the medical laboratory: CASA in diagnostic andrology and assisted conception. Reproduction, Fertility and Development 30(6) 850-859

  • Woodward B, Goosen N, Meadows J and Tomlinson MJ (2016) Uncertainty associated with assessing semen volume: are volumetric and gravimetric methods that different? .  Hum Fertil 19, 249-253.

  • Woodward B, Tomlinson MJ and Kirkman Brown J (2016). Replacing IUI with IVF for initial treatment of unexplained infertility: why this NICE recommendation is cause for concern. Human Fertility 19(2):1-5

  • Aljaser FS, Campbell BK, Almajed FS4 and Tomlinson MJ (2017). Efficacy of Ultra-Rapid Freezing by Direct Immersion into Liquid Nitrogen for Sperm Cryopreservation and Its Potential for Male Fertility Preservation. Int J Innov Res Med Sci (IJIRMS) 2, 10,   1401-1412.

  • Tomlinson MJ, Comajuan E, Naeem A and Pooley K (2016). Standards in reporting cryopreserved donor sperm characteristics: Should they be  reported post thaw or post wash? RBMonline, 33(1):111-113

  • Tomlinson MJ (2016). Debate : Uncertainty of measurement and clinical value of semen analysis: Has standardisation through professional guidelines  helped or hindered progress ?  Andrology,   4, 763-770.

  • Tomlinson MJ,  Meadows J, Kohut,Z, Haoula A, Naeem A, Pooley K and Deb S (2015). Review and follow-up of patients using a regional sperm cryopreservation service: ensuring that resources are targeted to those patients most in need.  Andrology. 3:709-16

  • Hancock R, Lindsay K, Tomlinson MJ (2014). Use of large-volume, fixed-depth, disposable slides for post-vasectomy semen analysis. Br J Biomed Sci. 2014;71(1):1-5.

  • Tomlinson MJ, Lewis S  and Morroll D (2013).  Sperm quality and its relationship to natural and assisted conception: British Fertility Society Guidelines for Practice. Human Fertility 16(3):175-93.

  • Tomlinson MJ, Harbottle SJ, Woodward BJ And Lindsay  K. Association Of Biomedical Andrologists – Laboratory Andrology Guidelines For Good Practice Version 3 – 2012. Human Fertility,  15(4): 156–173

  • Tomlinson MJ, Kohut T, Hopkisson JF and Lemberger RJ  Routine sperm banking for testicular cancer patients should be performed both before and after orchidectomy. J Clin Urol 2012;  6: 171-176

  • Pacey A, . Merrick, H, Arden-Close E, Morris K., Tomlinson, M, Wright, E. Rowe R, & Eiser, C (2012). Monitoring fertility (semen analysis) by cancer survivors who banked sperm prior to cancer treatment. Human Reproduction 27, 3132-3139

  • Tomlinson MJ, Naeem A, Hopkisson JF and Campbell B (2012) . Brief Communication: Assessment and validation of non-spermicidal condoms as specimen collection sheaths for semen analysis and assisted conception. Hum Fertil 15, 140-143

  • Tomlinson M (2010). Is your andrology service up to scratch. Human Fertility. 13, 194-200.

  • Tomlinson MJ, Pooley K, Pierce A and *Hopkisson JF (2010 . Sperm donor recruitment within an NHS fertility service since the removal of anonymity. Human Fertility 13, 159-167.

  • Tomlinson, MJ, Naeem A, Jayaprakasan K, Jayaprakasan R, Simpson, T, Newton T, Pooley K,  Hopkisson J and Pridmore (2010).  Validation of a novel computer assisted sperm analysis (CASA) system employing multi-target tracking algorithms. Fertility and Sterility 93(6):1911-20.

  • Association of Biomedical Andrologists; Association of Clinical Embryologists; British Andrology Society; British Fertility Society; Royal College of Obstetricians and Gynaecologists (2008). UK guidelines for the medical and laboratory screening of sperm, egg and embryo donors (2008). Hum Fertil (Camb). 2008;11(4):201-10.

  • Hamilton M, Pacey A, Tomlinson M, Brison D, Shaw L, Turner C, Witjens L, Morris P, Brown C, Montuschi O, Adams J, Lieberman B, Speirs J. Working Party on Sperm Donation Services in the UK: report and recommendations. Hum Fertil (Camb). 2008 Sep;11(3):147-58.

  • Tomlinson MJ (2008) Risk management in cryopreservation associated with assisted reproduction. Cryoletters, 29, 165-174.

  • Tomlinson MJ and Morroll D (2008). Risks associated with cryopreservation: a survey of assisted conception units in the UK and Ireland*. Human Fertility, 11, 33-42.

  • Bailey E, Fenning NR, Chamberlain S, Devlin L, Hopkisson JH and Tomlinson MJ (2007). Validation of sperm counting methods using Limits of Agreement. Journal of Andrology, 28, 364-373 .

  • Tomlinson MJ (2005) Opinion:  Managing Risk Associated with Cryopreservation. Human Reproduction, 20: 1751-1756.

  • Morrell J, Moffatt, Sakkas D O, ,Manicardi G, Bizarro D, Tomlinson MJ, Neilson H and Holmes PV (2004). Reduced senescence and retained nuclear DNA integrity in human spermatozoa prepared by density gradient centrifugation.  J Assisted Reprod and Genet 21, 217-222 (2004)

  • Bjorndahl L, Tomlinson MJ and Barratt CLR (2004). Raising standards in Semen Analysis: Professional and Personal responsibility. J Androl 25, 6, 156-157.

  • Tomlinson MJ and Pacey AA (2003). Practical Aspects of Sperm Banking for Cancer. Human Fertility 6, 100-105.

  • Moffatt O, Drury S, Tomlinson MJ, Afnan M and Sakkas D (2002). The apoptotic profile of human cumulus cells alters with patient age and after exposure to sperm but not in relation to oocyte maturity. Fertility Sterility 77, 5, 1006-1011.

  • Tomlinson MJ, Moffatt O, Manicardi G, Bizarro D, Afnan M and Sakkas D (2001). Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: Implications for assisted conception. Human Reproduction, 10, 2160-2165. 

  • Tomlinson MJ, Powell G, Turner J and Sakkas D (2001). One step disposable chambers for sperm concentration and motility assessment: How do they compare with the World Health Organization’s recommended methods? Human Reproduction. 16 1, 121-124.

  • Tomlinson MJ and Sakkas D (2001). Debate Article: Safe and effective cryopreservation: Should sperm banks and fertility centres move toward storage in nitrogen vapour? Human Reproduction 15, 2460-2463.

  • Sakkas D, Tomlinson M. Assessment of sperm competence. Semin Reprod Med 2000;18(2):133-9

  • Sakkas D, Manicardi GC, Tomlinson M, Mandrioli M, Bizzaro D, Bianchi PG, Bianchi U (2000). The use of two density gradient centrifugation techniques and the swim-up method to separate spermatozoa with chromatin and nuclear DNA anomalies. Human Reproduction 15, 1112-6.

  • Tomlinson MJ, Kessopoulou E & Barratt CLR (1999). The diagnostic and prognostic value of traditional semen parameters. Review. J Androl. 1999 Sep-Oct;20(5):588-93

  • Tomlinson MJ, Amissah-Arthur JB, Thompson KA, Kasraie J & Bentick B (1996). Prognostic indicators for IUI: Statistical model for IUI success. Human Reproduction. 11, 1892-1896.

  • Tomlinson MJ, Barratt CLR & Cooke ID (1993). Prospective study of leukocytes and leukocyte subpopulations in semen suggests they are not a cause of male infertility. Fertility & Sterility; 60: 1069-75.

  • Tomlinson MJ, Barratt CLR, Bolton AE, Lenton EA, Roberts HB, Cooke ID. Round cells and sperm fertilizing capacity: the presence of immature germ cells but not seminal leukocytes are associated with reduced success of in vitro fertilization. Fertility & Sterility 1992;58:1257-59.

  • Tomlinson MJ, White A, Barratt CLR, Bolton AE, Cooke ID (1992). The removal of morphologically abnormal sperm forms by phagocytes: a positive role for seminal leucocytes? Human Reproduction 1992;7:517-22.

  • Barratt CLR, Tomlinson MJ and Cooke ID (1993)  Prognostic significance of computerized motility analysis for in vivo fertility. Fertil Steril. 60(3):520-5.

  • Tomlinson MJ, East SJ, Barratt CLR, Bolton AE, Cooke ID. Possible role of reactive nitrogen intermediates in leucocyte-mediated sperm dysfunction. American Journal of Reproductive Immunology 1992;27:89-92.

  • Kessopoulou E, Tomlinson MJ, Barratt CLR, Bolton AE, Cooke ID. Origin of reactive oxygen species in human semen: spermatozoa or leucocytes. J Reprod Fertil 1992;94:463-70.

  • Barratt CLR, Kessopoulou E, Thompson LA, Tomlinson MJ & Cooke ID (1992). Review - Leucocytes in the male and female reproductive tracts. Reproductive medicine reviews; 1, 115-129.

  • Thompson LA, Tomlinson MJ, Barratt CLR, Bolton AE & Cooke ID. Positive immunoselection - method of isolating leucocytes from leucocytic reacted cervical mucus samples. American journal of reproductive Immunology 1991; 26:53-56.


  • Tomlinson ( 2019).  Diagnostic semen analysis: in Clinical Reproductive Science. .Michael Carooll Ed. DOI: 10.1002/9781118977231.ch22 Wiley Press P265-278

  •  Long S, Woodward B and Tomlinson MJ  (2017).Sperm toxicity testing: UK best practice guideline from the Association of Biomedical Andrologists. BJ Biomed Sci 75 2, 53-60

  • Tomlinson MJ, Harbottle SJ, Woodward B and Lindsay K. Association of Biomedical Andrologists (ABA). Guidelines for good practice version 3.

  • Tomlinson MJ and Harbottle SJ (2013). Facilities and Resources for the Andrology Service: In A Practical Guide to Setting Up an IVF Lab, pp69-86. Varghese A, Sjoblem P and Jayaprakasan K. Jaypee Medical Publishers

  • Tomlinson MJ (2010). Semen cryopreservation. In: Clinical Andrology: EAU/ESAU course guidelines. Editors Weidner W, Giwercman A, Tournaye H and Bjorndahl L.  Informa world

  • Pacey AA and Tomlinson MJ (2008). Sperm Banking Theory and Practice, (Eds).  Cambridge University Press

  • Tomlinson MJ (2008).  Sperm processing and storage. In: Sperm Banking Theory and Practice, Pacey AA and Tomlinson MJ (Eds).  Cambridge University Press

  • Tomlinson MJ and Pacey AA (2008).  Future developments for fertility preservation in men. In: Sperm Banking Theory and Practice, Pacey AA and Tomlinson MJ (Eds).  Cambridge University Press

  • Tomlinson MJ, Sakkas DS and Barratt CLR (2003). Semen Analysis and sperm function testing: in Grays Cytopathology. Harcourt Health Sciences.

  • Sakkas D, Manicardi G, Bizarro D, Moffatt O and Tomlinson MJ (2001). Paternal Effects on Fertilisation, Embryo Development and Pregnancy Outcome. In: ART and the Human Blastocyst. Gardener DK and Lane M (Eds). Proceedings of the Serono Symposium. Springer-Verlag, New York.

  • Sakkas D and Tomlinson MJ. Assessment of sperm competence: the assessment of sperm nuclei as an indicator. In: Novel Approaches to Assisted Reproduction: In Vitro Maturation of Gametes and Embryos. edited by D. Gardner, Z. Rosenwaks. Thieme Medical Publishers Inc. New York (in press)

  • Tomlinson MJ and Barratt CLR (2001) Royal College of Obstetricians and Gynaecologists. RCOG Dialog,

  • Tomlinson MJ & Barratt CLR (1999). Internal and External Quality Control in the Andrology laboratory: In: Handbook of the Assisted Reproduction Laboratory. CRC press. Keel BA, May JV and DeJonge CJ Eds 

  • Tomlinson MJ & Barratt CLR (2004). Donor Insemination. In: Good clinical practice in assisted conception. Cambridge University Press. Serhal P and Overton C (Eds)

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